Along with many other experts, I see little value in measuring fasting insulin. However, my reasons may differ to others. One reason is that fasting insulin does not generally reflect post-prandial insulin levels. Although we are not as bad as Hobbits for continuously eating, many of us spend more time in the post-prandial state than we do in the fasted state. This means that understanding our post-prandial insulin status has more meaning for our overall metabolic health than our fasting insulin levels.
From: An Unexpected Journey
Another challenge for using fasting insulin is understanding insulin secretion itself.
Insulin is released from the beta cells of the pancreas in a basal and bolus fashion. In the basal state, we maintain a low level of insulin in the blood, enough to maintain homeostasis. However, if blood glucose levels increase, a bolus of insulin is released in order to restore balance.
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